Study the profile of some antioxidant markers in diabetic mellitus and non-diabetic patients with cardiovascular disease

Medical Journal of Babylon

article

Israa Ghassan Zainal¹ 

[1] Department of Chemistry, College of Science, University of Kirkuk

关键词: Antioxidant markers;    cardiovascular diseases;    HAS;    IMA;    type 2 diabetes;   

DOI  :  10.4103/MJBL.MJBL_190_22

学科分类：社会科学、人文和艺术（综合）

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

Background: Cardiovascular diseases (CVDs) claim the lives of millions worldwide. Objective: Evaluate the levels of some antioxidant biomarkers in sera of patients with CVDs with and without diabetes mellitus type 2. Materials and Methods: Includes 100 samples in 68 patients (40 with CVDs and 28 CVDs with diabetic), and 32 healthy subjects. Results: Serum (Albumin, thiol, thiol/T.protein, amine, free amine/ T.protein, carbonyl, carbonyl/ T.protein, and Ischemia modified albumin (IMA)) showed a stronger response, a significant rise in carbonyl and carbonyl/TP, and a significant reduction in thiol and thiol/TP in the patients with CVDs with T2D compared to CVDs may be a good factor to differentiate them or predict more serious complications. Conclusions: Oxidation markers may be useful in monitoring CVDs with and without diabetes.

【 授权许可】

CC BY-NC-SA