Evaluation of antimicrobial action and push-out bond strength and compressive strength using mineral trioxide aggregate and triple antibiotic medicament combination as root-end filling material: A novel in vitro study

Endodontology

article

Begum, Raeesunisa¹  Halkai, Kiran R.¹  Ghatole, Kiran¹  Hambire, Ashwini¹  Ahmed, Amaan¹  Halkai, Rahul S.¹ 

[1] Department of Conservative Dentistry and Endodontics, Al-Badar Rural Dental College and Hospital, Kalaburagi

关键词: Antimicrobial activity;    compressive strength;    mineral trioxide aggregate;    push-out bond strength;    root-end filling;    triple antibiotic paste;   

DOI  :  10.4103/endo.endo_172_21

学科分类：材料科学（综合）

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

Aim:  The study aims to evaluate the antimicrobial properties and push-out bond and compressive strength of mineral trioxide aggregate (MTA) mixed with different ratios of triple antibiotic paste (TAP) against Enterococcus faecalis. Methodology:  Antimicrobial effect was evaluated using agar well diffusion method. Materials were divided into three groups. Group 1: MTA, Group 2: MTA + TAP (2:1 ratio), and Group 3: MTA + TAP (1:1 ratio) zone of inhibition were determined after 24 h of incubation at 37°C. To evaluate push-out bond strength, 30 extracted teeth were decoronated to a length of 13 mm, followed by root canal treatment, the root resected at 3 mm from the apex, and root-end cavity was prepared and filled. Cylindrical specimens (n = 10 per group) of size 3 mm × 6 mm were prepared of MTA, MTA plus triple antibiotic 2:1 and 1:1 ratio and tested for compressive strength using Instron Universal testing machine. All the data were statistically analysed using Krusal–Wallis test (P < 0.05). Results:  MTA + TAP (1:1 ratio) exhibited highest antimicrobial activity than MTA + TAP (2:1 ratio) and MTA alone. The push-out bond and compressive strength of Group 1 (MTA alone) was better compared to two groups containing MTA in combination with TAP; however, no statistical significant difference was found between the three groups. Conclusion:  Combination of TAP with MTA increases the antimicrobial activity against E. faecalis without compromising much of the compressive and push-out bond strength, hence can be advocated for root-end filling.

【 授权许可】

CC BY-NC-SA