Seed lost to perineum from hydrogel spacer after brachytherapy for prostate cancer

IJU Case Reports

article

Makoto Nakiri¹  Kosuke Ueda¹  Ryuji Hoshino¹  Naoyuki Ogasawara¹  Hirofumi Kurose¹  Kiyoaki Nishihara¹  Koichiro Muraki²  Chikayuki Hattori²  Etsuyo Ogo²  Tsukasa Igawa¹ 

[1] Department of Urology, Kurume University School of Medicine;Department of Radiology, Kurume University School of Medicine

关键词: brachytherapy;    hydrogels;    inflammation;    perineum;    prostate cancer;   

DOI  :  10.1002/iju5.12579

学科分类：社会科学、人文和艺术（综合）

来源: Wiley

【 摘 要 】

IntroductionWe describe a rare case of brachytherapy for prostate cancer in which a seed was lost from the perineum after a hydrogel injection. Case presentationA 71-year-old Japanese man was diagnosed with localized high-risk prostate cancer. Trimodality therapy with I-125 brachytherapy was selected, and combined androgen blockade therapy was initiated. Brachytherapy and hydrogel injection were performed 7 months after combined androgen blockade initiation; 6 months later, the patient visited our hospital with complaints of redness and bleeding in the perineum. Serous effusion and loss of a seed on the right side of the perineal anus were observed. Pelvic magnetic resonance imaging showed a tunnel like discharge of hydrogel from the dorsal prostate to the perineum. The fistula was incised, the seed was removed, and drainage was performed. ConclusionAppropriate diagnosis and treatment with careful follow-up are required in patients at high risk of infection after brachytherapy with hydrogel injection.

【 授权许可】

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