IJU Case Reports | |
Metastatic small-cell carcinoma of the bladder that maintains a complete response to chemoradiation therapy | |
article | |
Shinya Miyazaki1  Takashi Ueda2  Ryosuke Tamai1  Akihisa Ueno1  Terukazu Nakamura1  | |
[1] Department of Urology, Saiseikai Suita Hospital;Department of Urology, Kyoto Prefectural University of Medicine | |
关键词: carboplatin; irinotecan; radiation; small cell carcinoma; urinary bladder; | |
DOI : 10.1002/iju5.12547 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Wiley | |
【 摘 要 】
IntroductionSmall-cell carcinoma of the urinary bladder has a poor prognosis, and no standard treatment has been established. We encountered a case of a patient with metastasis in which complete response and long-term survival were obtained by treating the primary lesion with a combination of irinotecan, carboplatin chemotherapy, and radiation therapy. Case presentationAn 83-year-old man was diagnosed with a bladder tumor with liver metastasis. Small-cell carcinoma was diagnosed via transurethral resection. Second-line chemotherapy with irinotecan and carboplatin and irradiation of the primary lesion were significantly effective. The imaging evaluation showed a complete response. The therapeutic effect was maintained for 1 year, even after the discontinuation of chemotherapy. ConclusionIrinotecan and carboplatin should be considered for the treatment of small-cell carcinoma of the bladder. Irradiation of the primary lesion may also be useful if the extent of metastasis is low.
【 授权许可】
CC BY|CC BY-NC|CC BY-NC-ND
【 预 览 】
Files | Size | Format | View |
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RO202307080005075ZK.pdf | 730KB | download |