The added prognostic values of baseline PET dissemination parameter in patients with angioimmunoblastic T-cell lymphoma

eJHaem

article

Huanyu Gong¹  Bo Tang²  Tiannv Li¹  Jianyong Li³  Lijun Tang¹  Chongyang Ding¹ 

[1] Department of Nuclear Medicine, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University;Department of Radiology, Shuyang Hospital of Traditional Chinese Medicine;Department of Hematology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University

关键词: angioimmunoblastic T-cell lymphoma;    dissemination;    FDG;    positron emission tomography;    prognosis;   

DOI  :  10.1002/jha2.610

来源: Wiley

【 摘 要 】

To explore the prognostic values of baseline 2-deoxy-2-[18456.6 cm3) was only significant for OS. A concise PET model based on TMTV and Dmax can effectively risk-stratify patients. PFS and OS rates were significantly lower in patients with high Dmax and high TMTV than in patients with low Dmax and low TMTV (3-year PFS rate: 15.0% vs. 48.7%, p = 0.001; 3-year OS rate: 27.6% vs. 79.0%, p < 0.001). Dmax can directly reflect the disease dissemination characteristic and has a significant prognostic value for FDG-avid AITL patients. It has the potential to be introduced into new risk stratification models for tailored treatment.

【 授权许可】

Unknown