Sporothrix brasiliensis infectando felinos no nordeste do Brasil: novas áreas emergentes no estado da Paraíba

Ciencia Rural

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Débora Ferreira dos Santos Angelo¹  Vanessa Brito de Souza Rabello²  Maria Adrielle Soares Maciel¹  Sheilla Suellenn de Lemos Araújo Atanázio¹  Maria Clara Lima da Costa¹  Suely Ruth Silva³  Rodrigo Almeida-Paes²  Andréa Reis Bernardes-Engemann²  Rosely Maria Zancopé-Oliveira²  Inácio José Clementino¹ 

[1] Universidade Federal da Paraíba;Instituto Nacional de Infectologia Evandro Chagas-Fundação Oswaldo Cruz;Centro de Vigilância Ambiental e Zoonoses

关键词: sporotrichosis;    geographic expansion;    cats;    molecular identification;   

DOI  :  10.1590/0103-8478cr20220351

学科分类：农业科学（综合）

来源: Universidade Federal de Santa Maria * Centro de Ciencias Rurais

【 摘 要 】

Sporotrichosis is a subcutaneous mycosis caused by fungus of the Sporothrix complex, and in Brazil the main species reported is Sporothrix brasiliensis, of which the diseased cat is the transmitter. Although, its occurrence has increased in the state of Paraíba, Brazil, since 2016, data on the disease in this state are limited. Therefore, this research aimed to identify molecularly isolates of Sporothrix spp. from domestic cats from cities in Paraíba, and in this way to expand the understanding of the disease in the state. Thirty-nine samples were analyzed, obtained from skin lesions of domestic felines, from the following cities in Paraíba: João Pessoa, Pilões, Patos, Areia, Bananeiras and Guarabira. Cytological analysis was performed to screen the samples, followed by fungal culture, and the molecular characterization of the isolates was performed, using the species-specific Polymerase Chain Reaction (PCR) or partial sequencing of the calmodulin gene. All isolates were identified as S. brasiliensis. The sequencing showed 100% similarity to the S. brasiliensis CBS 120339 strain. In view of this, it is concluded that in the study areas the species involved in cases of feline sporotrichosis is S. brasiliensis, its presence in Paraíba demonstrated the spread of the agent in regions distant from the epicenters in Brazil, alerting to the possible occurrence of zoonotic outbreaks similar to those found in the South and Southeast regions of the country. In addition, it highlights the emerging role of felines in the transmission of sporotrichosis in new endemic areas of Brazil.

【 授权许可】

Unknown