Attitudes toward Rubella and Varicella Vaccination during Preconception Care

Kansas Journal of Medicine

article

Elise Foley¹  Shelby Breit²  Courtney Marsh¹  Kevin Ault²  Michael Lydic³ 

[1] University of Kansas;University of Kansas School of Medicine-Salina;University of Kansas Medical Center

关键词: Vaccine attitudes;    Preconception care;    MMR Vaccine;    Varicella Vaccine;   

DOI  :  10.17161/kjm.vol14.15205

学科分类：医学（综合）

来源: The University of Kansas Medical Center

【 摘 要 】

Introduction. MMR and Varicella vaccines contain live attenuated virus, a contraindication during pregnancy. For this reason, it is important to clinically assess barriers to vaccination during the preconception time period to avoid the known fetal morbidity associated with congenital Rubella or Varicella infection. Methods. To determine the prevalence of patients with nonimmune status for Rubella and Varicella in the setting of advanced reproductive care. Secondary outcomes of interest included further understanding nonimmune reproductive-aged women's attitudes toward MMR and Varicella vaccination during the preconception time frame. Patient records were with lab orders for Rubella or Varicella immunoglobulin titers, placed at the KU Advanced Reproductive Care clinic between January 2017 and June 2020. A cross-sectional survey was administered to patients with a laboratory reported negative titer result. Results. Prevalence of nonimmunity within the study population to either Rubella and/or Varicella was 10.7% (n=1,979), to Rubella, 6.0% (n=134) and to Varicella, 3.8% (n=85) out of a total 2,217 patient records reviewed. The women who did not receive recommended vaccines following a nonimmune titer result (n=19) most commonly cited their rationale was to not further delay fertility treatment (n=8). Conclusions. The prevalence of nonimmune persons in the study population fell within the range recognized to be sufficient for herd immunity. The risk/benefit analysis of postponing fertility treatment to achieve adequate levels of immunity should be a focused discussion when establishing fertility treatment goals with patients in the setting of advanced reproductive care.

【 授权许可】

Unknown