The Relationship Between Functional Dyspepsia, PPI Therapy, and the Gastric Microbiome

Kansas Journal of Medicine

article

Balaji Jagdish¹  Dr. William Ransom Kilgore III² 

[1] Kansas City University School of Medicine and Biosciences;University of Kansas School of Medicine-Wichita

关键词: PPI Therapy and Gastritis;    Streptococcus species;    Gut Microbiome;   

DOI  :  10.17161/kjm.vol1414831

学科分类：医学（综合）

来源: The University of Kansas Medical Center

【 摘 要 】

Dyspepsia refers to symptoms originating from the gastroduodenalregion and includes etiologies such as gastroesophageal reflux, hiatalhernias, peptic ulcers, H. pylori infections, erosive gastritis, and gastroesophageal malignancy.1,2 Symptomology often varies, but may includenausea, vomiting, heartburn, dysphagia, and chest pain. Dyspepsiaaffects about 40% of the general population and etiologies often canbe diagnosed with the use of esophagogastro-duodenoscopy (EGD).3Despite the use of EGDs, 70% of patients diagnosed with dyspepsiaare negative for any structural or infectious (i.e., H. pylori) etiology.4 Insuch patients, the diagnosis of functional dyspepsia (FD) often is made.

【 授权许可】

Unknown