期刊论文详细信息
Resonance
Connecting Biology With Biotechnology: Industrial Applications of Adaptive Laboratory Evolution
article
Komal Kadam1  Ram Kulkarni1 
[1]Symbiosis School of Biological Sciences, Symbiosis International ,(Deemed University)
关键词: Adaptive laboratory evolution (ALE);    lactic acid bacteria (LAB);    reverse engineering;    genetic engineering.;   
DOI  :  10.1007/s12045-022-1469-0
学科分类:社会科学、人文和艺术(综合)
来源: Springer
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【 摘 要 】
Adaptive laboratory evolution (ALE) has been used as a tool to understand the basic principles of evolution as well as for engineering microorganisms for numerous industrial applications. With recent advances in next-generation sequencing (NGS), ALE has regained its momentum, and it has become possible to identify underlying causal mutations. Thus, ALE can serve as a tool for imparting industrially useful features in the microbes and complement the genetic engineering approaches.
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