Evaluating the Efficacy of the Er,Cr:YSGG Fractional Laser Before Treatment With Triamcinolone NN Ointment in Oral Lichen Planus Lesions

Journal of Lasers in Medical Sciences

article

Hamid Rezakhalighi¹  FahimehAnbari¹  Seyed MasoudMojahedi²  Gelareh Forouzani³ 

[1] Department of Oral Medicine, Dental Faculty, Shahid Beheshti University of Medical Sciences;Senior Research Fellow at Bonn University;Department of Oral Medicine, Dental Faculty, Aja University of Medical Sciences

关键词: Oral lichen planus;    Corticosteroid;    Laser;    Er;    Cr:YSGG;   

DOI  :  10.34172/jlms.2022.23

学科分类：基础医学

来源: Shahid Beheshti University of Medical Sciences

【 摘 要 】

Introduction: It has been demonstrated that laser technology can enhance topical drug absorption. This study aimed to determine the effects of Er, Cr: YSGG laser radiation before the application of topical corticosteroids in the healing of oral lichen planus.Methods: In this double-blind split-mouth clinical trial, 32 lesions were chosen from eight patients affected by oral lichen planus (OLP). The oral lesions were randomly categorized into two groups. The first group had topical treatment with triamcinolone NN ointment and the second group had laser radiation (Er,Cr:YSGG) for eight weeks before starting the ointment. For each lesion, the irritating level based on the VAS score, the lesion level based on the Thongprasom scale score, and the healing time were measured, and the collected data were analyzed by the Friedman test and the Wilcoxon’s statistical test.Results:0.05).Conclusion: The application of the Er,Cr:YSGG laser before treatment with triamcinolone NN ointment did not show any advantage for the average healing time compared to a medicine regimen with only triamcinolone NN ointment.

【 授权许可】

CC BY