An Immunological Argument for One Health

American Journal of Immunology

article

Mark Brown¹  Mai Awad³  Christian Schmidt⁴ 

[1] Department of Clinical Sciences, Colorado State University;Department of Epidemiology Section, Colorado School of Public Health;Graduate Degree Program in Ecology, Colorado State University;Department of Biomaterials and Healthcare, Division of Life Science and Bioprocesses, Fraunhofer-Institute for Applied Polymer Research

关键词: Heavy Metals;    Lead;    Cadmium;    Autoimmunity;    Tumorigenesis;   

DOI  :  10.3844/ajisp.2022.5.8

学科分类：过敏症与临床免疫学

来源: Science Publications

【 摘 要 】

Human exposure to heavy metals is associated with higher ratesof immunological deficiencies, autoimmunity, and cancer. Chronicexposure to lead contributes to abnormalities in immunomodulationwhile cadmium is linked to breast, prostate, and lung cancers. Prenatalexposure to these metals impacts both the development and function ofimmune cells. The concept of one health underscores the importance ofthe interface between human, animal, and environmental health. Herein,we highlight heavy metal exposure via honey consumption as an exampleof the critical intersection of these factors as they relate to immunologicalimpacts and downstream pathologies.

【 授权许可】

CC BY