Comparison of outcome of Cartilage Perichondrium Composite Graft with Temporalis Fascia Graft in Type I Tympanoplasty in mucosal type of Chronic Otitis Media, A Randomized Cohort study.

Research Journal of Pharmaceutical, Biological and Chemical Sciences

article

Nitin Deosthale¹  Prajakta Golhar²  Sonali Khadakkar¹  Ananyan Sampath³  Varma Rahul Mahesh.⁴ 

[1] NKP Salve Institute of Medical Sciences & Research Centre and Lata Mangeshkar Hospital;Department of ENT, Datta Meghe Medical College;Undergraduate Medical Student, AIIMS;Department of ENT-HNS, AIIMS Bhopal

关键词: Otitis Media;    Hearing Loss;    Tympanoplasty;    Cartilage;    Fascia;    Pure Tone Audiometry.;   

DOI  :  10.33887/rjpbcs/2023.14.1.24

学科分类：工程和技术（综合）

来源: Research Journal of Pharmaceutical, Biological and Chemical Sciences

【 摘 要 】

Chronic Otitis Media (COM) is the major cause, responsible for deafness in India.1 According toWHO, the Western Pacific and Southeast Asian regions contribute about 85-90% of the global burden ofchronic otitis media, with India and China accounting for much of the burden. This was a RandomizedCohort of two years duration conducted after getting approval from Institutional Ethics Committee. Total88 patients of mucosal type of Chronic Otitis Media (COM) who underwent for Type I Tympanoplastywere included in the study. They were divided into Cartilage Group (Cartilage perichondrium compositegraft) and Fascia Group B (Temporalis fascia graft) with 44 patients in each group. Graft uptake rate andaudiological improvement at the end of 3 months follow-up was compared between two groups. MeanAge of Cartilage group was 30.45 + 9.85 years and that of Temporalis fascia group was 32.45 + 9.03 years.Graft uptake rate in cartilage group, was 90.9% and that in Fascia group, it was 86.36%.Improvement inhearing (ABG closure) in Cartilage group was 10.15 ± 2.24dB and that in temporalis fascia group was10.83 ± 2.60 dB. The difference in graft uptake and hearing gain between two the groups after 3 monthsof surgery was statistically insignificant (P

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