The Contemporary Analytical Observations Of Renal Biopsy Findings In Type 2 Diabetic Patients.

Research Journal of Pharmaceutical, Biological and Chemical Sciences

article

Alaudeen¹  Rajeev H¹  Sunil¹  Megha Shashidhar Handral.¹ 

[1] Department of General Medicine

关键词: Renal Biopsy;    Type 2 Diabetes Mellitus;    Non diabetic kidney disease;   

DOI  :  10.33887/rjpbcs/2022.13.5.1

学科分类：工程和技术（综合）

来源: Research Journal of Pharmaceutical, Biological and Chemical Sciences

【 摘 要 】

One of the most common causes of end-stage kidney disease is diabetic kidney disease (DKD).People with diabetes have a lower rate of kidney biopsies; nonetheless, these patients can haveglomerular disorders other than diabetic nephropathy. The quantity and complexity of renal biopsiesdone on diabetes individuals is growing. The purpose of this study was to evaluate into the utility of renalbiopsy in diabetic patients as well as the accuracy of distinguishing diabetic nephropathy (DN) versus nondiabetic renal disease (NDRD) using clinical and laboratory data. This was a single-center, cross-sectional,retrospective study on 100 patients to determine clinical and laboratory characteristics in all diabeticpatients who underwent biopsy at KIMS Hospital, Bangalore. This study consisted of 57 males and 43females with the mean age of 45.57 ± 14.34 years. On biopsy, we observed 40 patients with DN alone, 40patients with NDRD alone and around 20 patients has DN over-imposed with NDRD. The DN group had ahigher mean serum creatinine level of 3.10 mg/dl, followed by the DN over-imposed with NDRD and theNDRD alone group. The high Emerging prevalence of NDRD in our population emphasizes the importanceof clinicians considering renal biopsy in diabetic patients with an atypical clinical history, as extradisease-specific therapy may be beneficial for this subset of the population.

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