Evaluation Of Mobile Applications For The Detection Of Potencial Drug Interactions.

Research Journal of Pharmaceutical, Biological and Chemical Sciences

article

Dariel Antônio Spaki¹  Roberto Kenji Nakamura Cuman.² 

[1] Master in Health Sciences at the State University of Maringá;State University of Maringá, Post graduate Program in Health Sciences

关键词: Rheumatoid arthritis;    Drug interactions;    Adverse drug reactions;    Mobile apps;    Older persons;   

DOI  :  10.33887/rjpbcs/2021.12.4.2

学科分类：工程和技术（综合）

来源: Research Journal of Pharmaceutical, Biological and Chemical Sciences

【 摘 要 】

In chronic diseases, such as rheumatoid arthritis (RA), the affected patients tend to have a higherrisk of developing comorbidities and demand therapy with a wide variety of drugs (polypharmacy), so thephenomenon of drug interactions can arise in people with RA. The aim of this study was to analyze theavailable mobile applications which presented the functionality of drug interactions and adverse drugreactions. The sample consisted of 23 adults diagnosed with RA. Of the 1030 drugs distributed by thepharmacy, only the ten most frequent drugs were compared in pairs in three applications. The mean ageof the patients was 59.4 years, with a median of 61 years. The vast majority of patients were women, 20(87%). A greater risk was observed for the variables: family member with cardiovascular disease (Oddsratio=1.87) and allergic reaction to drugs or food (Odds ratio=1.55). A predominance of potential severerisk for drug interactions (20 alerts) was observed. The Drugs.com app was the most sensitive. It wasconcluded that the use of these devices for decision making as an instrument for prescription andtherapeutic follow-up should be used in the older persons with rheumatoid arthritis.

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