期刊论文详细信息
Journal of Thoracic Disease
Utilizing computed tomography volumetry for size matching prior to lung transplantation: a case series
article
Hailey M. Shepherd1  Khashayar Farahnak1  M. Shea Harrison1  C. Corbin Frye1  Gary F. Marklin2  Andrew J. Bierhals3  Ramsey R. Hachem4  Chad A. Witt4  Rodrigo V. Guillamet4  Derek E. Byers4  Benjamin D. Kozower1  Bryan F. Meyers1  Ruben G. Nava1  G. Alexander Patterson1  Daniel Kreisel1  Varun Puri1 
[1] Department of Surgery, Washington University School of Medicine;Mid-America Transplant;Departments of Radiology, Washington University School of Medicine;Departments of Medicine, Washington University School of Medicine;Departments of Pathology and Immunology, Washington University School of Medicine
关键词: Lung transplantation (LT);    size matching;    organ allocation;    case series;   
DOI  :  10.21037/jtd-22-1203
学科分类:呼吸医学
来源: Pioneer Bioscience Publishing Company
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【 摘 要 】

Background: Appropriate size matching between donor and recipient is critical for successful pulmonary transplantation. Although surrogate measurements such as height and gender are often utilized to approximate predicted lung volume, these methods provide only a gross estimation with wide variability and poor predictive value. Case Description: A single center exploratory study was conducted in which four patients underwent lung transplantation (LT) with pre-operative computed tomography (CT) volumetry obtained in both the donor and recipient to facilitate decision making regarding organ size and suitability. In four cases in which CT volumetry was used, the lung volumes calculated using surrogate measurements significantly overestimated both donor and recipient lung volumes quantified by CT volumetric analysis. All recipients underwent successful LT without necessary graft downsizing. Conclusions: This is an initial report of prospectively utilizing CT volumetry as an adjunct to decision-making regarding suitability of donor lungs. In these cases, CT volumetry facilitated the confident acceptance of donor lungs that were initially predicted to be oversized based on other clinical measures.

【 授权许可】

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