A narrative review of progress in airway stents

Journal of Thoracic Disease

article

Sen Tian¹  Haidong Huang¹  Zhenli Hu¹  Yuchao Dong¹  Chong Bai¹ 

[1]Department of Respiratory and Critical Care Medicine, Shanghai Changhai Hospital, the First Affiliated Hospital of Second Military Medical University

[2]Department of Biomedical Engineering, University of Shanghai for Science and Technology

关键词: Airway stents;    silicone stents;    metallic stents;    airway stenosis;   

DOI  :  10.21037/jtd-21-1871

学科分类：呼吸医学

来源: Pioneer Bioscience Publishing Company

【 摘 要 】

Background and Objective: Airway stents, used to restore airway patency, are mostly utilized by patients with malignant airway strictures, and are occasionally used in a range of other airway related diseases, including conditions which result in benign stenosis, malacia, and fistula. There has been an increasing number of airway stents that are being developed thanks to improvements in interventional therapy. However, the method of promoting airway stents for clinical application remains undetermined. Herein, we describe the recent advances in airway stents by reviewing the published studies, providing the reference for clinical decision-making and further research on airway stents. Methods: Relevant articles between January 1964 and November 2021 were obtained from PubMed, Web of Science, and EMBASE databases. The terms “metallic”, “silicone”, “drug-eluting", “biodegradable”, “radioactive”, “three-dimensional (3D)”, and “stents” were searched in different combinations. Key Content and Findings: In this review, we focus on the latest evidence in terms of the application of various stents with novel materials and designs including novel metallic, novel silicone, drug-eluting, biodegradable, radioactive, and 3D stents for airway stenosis. Despite reducing the well-known complications of all current commercially available stents, novel stents are still in their infancy without a long track record of utility and safety, and remain some limitations. There are more steps to be taken before such stents enter routine clinical practice. Conclusions: A combination of 3D-printing method and biodegradable material may present a promising avenue of solving the existing problems pertaining to “classic” stents and has potential to become the main trend in the future.

【 授权许可】

Unknown