The new allocation era and policy

Journal of Thoracic Disease

article

Luke J. Benvenuto¹  Selim M. Arcasoy¹ 

[1] The Lung Transplant Program, New York-Presbyterian Hospital and Columbia University Irving Medical Center, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine

关键词: Lung allocation;    policy;    geographic disparities;    lung transplantation;   

DOI  :  10.21037/jtd-2021-17

学科分类：呼吸医学

来源: Pioneer Bioscience Publishing Company

【 摘 要 】

Since the Department of Health and Human Services (DHHS) issued the Final Rule in 1998 as a guideline for organ transplantation and allocation policies, the lung allocation system has undergone two major changes. The first change came with the implementation of the lung allocation score (LAS) instead of waiting time as the primary determinant for donor lung allocation. The LAS model helped allocate donor lungs based on medical urgency and likelihood of post-transplant success. The LAS has been successful in prioritizing the sickest candidates and reducing waitlist mortality in line with the Final Rule mandates. However, the LAS model did not address geographic variability in donor lung supply and demand, leading to disparities in waiting list survival based on a patient’s listing location, which was inconsistent with the Final Rule. In an urgent response to a lawsuit filed by a patient demanding broader geographic access to lungs in November 2017, the second major change in lung allocation occurred when the primary allocation unit for donor lungs expanded from the local donation service area (DSA) to a 250-nautical mile radius around the donor hospital. The Organ Procurement and Transplantation Network has since undergone a review of the current organ allocation systems and has approved a continuous organ distribution framework to guide the creation of a new organ allocation system without rigid geographic borders. In this review, we will describe the history of lung allocation, the changes to the allocation system and their consequences, and the potential future of lung allocation policy in the U.S.

【 授权许可】

Unknown