Faecalibacterium prausnitzii is not decreased in symptomatic uncomplicated diverticular disease of the colon

Bioscience of Microbiota, Food and Health

article

Antonio TURSI¹  Paola MASTROMARINO³  Daniela CAPOBIANCO³  Walter ELISEI⁴  Giuseppe CAMPAGNA⁵  Marcello PICCHIO⁶  GianMarco GIORGETTI⁷  Federica FABIOCCHI⁷  Giovanni BRANDIMARTE⁸ 

[1]Territorial Gastroenterology Service

[2]Department of Medical and Surgical Sciences, Catholic University

[3]Department of Public Health and Infectious Diseases, Section of Microbiology, Sapienza University

[4]Division of Gastroenterology, S. Camillo-Forlanini Hospital

[5]Department of Experimental Medicine, Sapienza University

[6]Division of Surgery, P. Colombo Hospital

[7]Digestive Endoscopy and Nutrition Unit, S. Eugenio Hospital

[8]Division of Internal Medicine and Gastroenterology, Cristo Re Hospital

关键词: diverticular disease;    fecal microbiota;    Faecalibacterium prausnitzii;   

DOI  :  10.12938/bmfh.2022-046

学科分类：生物科学（综合）

来源: Nihon Bifizusukin Senta / Japan Bifidus Foundation

【 摘 要 】

In this letter, assessment of the amount of fecal Faecalibacterium prausnitzii in symptomatic uncomplicated diverticular disease (SUDD) is described. Among 44 consecutive patients, comprising 15 SUDD patients, 13 patients with asymptomatic diverticulosis (AD), and 16 healthy controls (HC), the fecal amount of Faecalibacterium prausnitzii was not found to be significantly different between HC, AD and SUDD subjects (p=0.871). Moreover, its count in the HC microbiota (−4.57 ± 2.15) was lower compared with those in the AD (−4.11 ± 1.03) and SUDD subjects (−4.03 ± 1.299). This behavior seems to be different from that occurring in inflammatory bowel disease (IBD) and similar to that of other mucin-degrading species in a SUDD setting.

【 授权许可】

CC BY