期刊论文详细信息
Japanese journal of infectious diseases
Influenza A Virus Infection in Domestic Ferrets
article
Yudai Kuroda1  Ai Okada1  Hiroshi Shimoda1  Yasutsugu Miwa3  Akiko Watamori3  Hiroho Ishida4  Shin Murakami4  Ayato Takada5  Taisuke Horimoto4  Ken Maeda1 
[1] Department of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University;Department of Veterinary Science, National Institute of Infectious Diseases;Miwa Exotic Animal Hospital;Department of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo;Global Institution for Collaborative Research and Education, Global Station for Zoonosis Control, Hokkaido University
关键词: ferret;    influenza;    seroprevalence;    reverse zoonosis;   
DOI  :  10.7883/yoken.JJID.2021.745
学科分类:传染病学
来源: National Institute of Infectious Diseases
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【 摘 要 】

Ferrets are animals that are known to be susceptible to influenza A virus (IAV) infection. To evaluate the risk of IAV transmission from diseased ferrets to humans, a survey was performed to detect specific antibodies against the H1, H3, H5, and H7 subtypes of IAV. Using enzyme-linked immunosorbent assay for hemagglutinin proteins, we found a high positive rate for the H1 (24.1%) and H3 (5.2%) subtypes. The results were confirmed by a virus neutralization test for representative antibody-positive serum samples. We also detected hemagglutinin and neuraminidase genes in two ferrets showing acute respiratory disease and whose owner was diagnosed with IAV infection; a human H1N1pdm virus was isolated from one of these ferrets. Our findings suggest that attention should be paid to IAV infection from humans to ferrets and vice versa.

【 授权许可】

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