Rescuing the right ventricle: A conceptual framework to target new interventions for patients receiving a durable left ventricular assist device

The Journal of Thoracic and Cardiovascular Surgery

article

Michael J. Pienta¹  Pierre-Emmanuel Noly¹  Allison M. Janda²  Paul C. Tang¹  Abbas Bitar³  Michael R. Mathis²  Keith D. Aaronson³  Francis D. Pagani¹  Donald S. Likosky¹ 

[1] Section of Health Services Research and Quality, Department of Cardiac Surgery, Michigan Medicine;Department of Anesthesiology, Michigan Medicine;Division of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine

关键词: right heart failure;    left ventricular assist device;    hemodynamics;    conceptual framework;   

DOI  :  10.1016/j.jtcvs.2022.03.025

学科分类：心脏病和心血管学

来源: Mosby, Inc.

【 摘 要 】

Right heart failure (RHF) is a frequent comorbid condition in patients being evaluated for durable, left ventricular assist device (LVAD) therapy. RHF is defined by the incapacity of the right ventricle (RV) to provide adequate cardiac output to the LV and LVAD device and is associated with poor systemic perfusion resulting in renal and hepatic failure, venous and hepatic congestion causing bleeding requiring transfusion, and increased risk of mortality.1 RHF occurs when the RV function is no longer adapted to the loading conditions because of intrinsic RV dysfunction; elevated pulmonary vascular resistance; or more commonly, a combination of both.

【 授权许可】

Unknown