Full-Digital Customized Meshes in Guided Bone Regeneration Procedures: A Scoping Review

Prosthesis

article

Andrea Scribante¹  Martina Ghizzoni¹  Matteo Pellegrini²  Federica Pulicari²  Mattia Manfredini²  Pier Paolo Poli²  Carlo Maiorana²  Francesco Spadari² 

[1] Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia;Maxillofacial Surgery and Dental Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico;Department of Biomedical, Surgical and Dental Sciences, University of Milan

关键词: CAD/CAM;    customized mesh;    dentistry;    digital workflow;    GBR;    guided bone regeneration;    oral surgery;    PEEK;    titanium mesh;    3D printing;   

DOI  :  10.3390/prosthesis5020033

学科分类：自然科学（综合）

来源: mdpi

【 摘 要 】

Meshes, especially titanium ones, are being widely applied in oral surgery. In guided bone regeneration (GBR) procedures, their use is often paired with membranes, being resorbable or non-resorbable. However, they present some limitations, such as difficulty in the treatment of severe bone defects, alongside frequent mesh exposure. Customized meshes, produced by a full-digital process, have been recently introduced in GBR procedures. Therefore, the focus of the present review is to describe the main findings in recent years of clinical trials regarding patient-specific mesh produced by CAD/CAM and 3D printing workflow, made in titanium or even PEEK, applied to GBR surgeries. The purpose is to analyze their clinical management, advantages, and complications. This scoping review considered randomized clinical trials, observational studies, cohort studies, and case series/case reports studies. Studies that did not meet inclusion criteria were excluded. The preferred reporting items for scoping reviews (PRISMA-ScR) consensus was followed. A total of 15 studies were selected for this review. Based on the studies included, the literature suggests that meshes produced by a digital process are used to restore complex and severe bone defects. Moreover, they give satisfactory aesthetic results and fit the defects, counteracting grid exposure. However, more clinical trials should be conducted to evaluate long-term results, the rate of complications, and new materials for mesh manufacturing.

【 授权许可】

CC BY