One Health Approach to Leptospirosis: Human–Dog Seroprevalence Associated to Socioeconomic and Environmental Risk Factors in Brazil over a 20-Year Period (2001–2020)

Tropical Medicine and Infectious Disease

article

Natacha Sohn-Hausner¹  Louise Bach Kmetiuk¹  Alexander Welker Biondo¹ 

[1] Department of Cell and Molecular Biology, Federal University of Paraná

关键词: public health;    one health;    risk factors;    sentinels;    zoonosis;   

DOI  :  10.3390/tropicalmed8070356

学科分类：社会科学、人文和艺术（综合）

来源: mdpi

【 摘 要 】

Despite being considered a neglected, re-emerging and the most widespread zoonotic disease worldwide, human-dog leptospirosis has not been subjected to One Health approach, and neither were its socioeconomic and environmental risk factors, as well as concomitant spatial analysis over time. Accordingly, notified human leptospirosis cases, incidence rate and urban hotspot areas, in addition to a systematic review of dog leptospirosis cases, were performed nationwide from 2001 to 2020 in Brazil. Data on Gross Domestic Product (GDP), flooding and study areas were also assessed and tabulated. Human–dog leptospirosis cases were simultaneously mapped with overlapping flooding areas, along with the main circulant serovars. Comparative outcome has shown that dogs may be exposed similarly to humans, becoming important sentinels and/or reservoirs for human leptospirosis in larger geographic areas. Moreover, the study herein can help in the decision and implementation of public policies in Brazil and may serve as a model for other tropical countries worldwide.

【 授权许可】

CC BY