Isolation and Purification of Single Gold Nanoclusters by Alternate Pumping Chromatography

Separations

article

Malvina Supper¹  Virginia Birner¹  Lukas Gromotka²  Wolfgang Peukert²  Malte Kaspereit¹ 

[1] Institute for Separation Science & Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg;Institute of Particle Technology, Friedrich-Alexander-Universität Erlangen-Nürnberg

关键词: nanoparticles;    nanoclusters;    chromatography;    recycling;    alternate pumping;   

DOI  :  10.3390/separations10030214

学科分类：社会科学、人文和艺术（综合）

来源: mdpi

【 摘 要 】

Alternate pumping chromatography is applied to obtain atomically precise glutathione-stabilized gold nanoclusters in high purity from synthesized mixtures. On the basis of anion exchange chromatography, the feasibility of isolating a single cluster, Au10GSH10, as well as two different clusters simultaneously (Au25GSH18 and Au29GSH20) is demonstrated. In addition, Au18GSH14, which is present only in trace amounts, is successfully enriched. A simple design procedure is proposed that allows using columns with different retention behavior. Successful experiments with large injection amounts confirm the potential of the concept for preparative-scale productions of high-quality nanoparticulate products.

【 授权许可】

CC BY