Investigation of serum Amyloid A, haptoglobin andfibrinogen levels in sheep infected with Fasciola hepatica

Journal of Livestock Science

article

V. Denizhan¹  S. Kozat²  A.B. Yilmaz³ 

[1] Medical Laboratory Techniques Dept., Özalp Vocational School;Department of internal diseases, Faculty of veterinary;Midwifery Department, Van Health Vocational School, Van Yuzuncu Yil University, Zeve Campus

关键词: sheep;    Fasciola hepatica;    haptoglobin;    serum Amyloid A;    fibrinogen;   

DOI  :  10.33259/JLivestSci.2019.53-58

学科分类：农业科学（综合）

来源: Journal of Livestock Science

【 摘 要 】

The present study aimed to determine the changes in serum haptoglobin, serum amyloid A and fibrinogen levels inpathological disorders of sheep liver with Fasciola hepatica. Sixty sheep (50 with fascioliasis and 10 healthy) were used inthe present study. Statistical analysis results demonstrated that SAA, Hp and fibrinogen concentration levels of the sheepinfected with Fasciola hepatica were higher when compared to SAA, Hp and fibrinogen concentration levels in healthysheep (P <0.05). While ALT, AST and GGT values of sheep infected with Fasciola hepatica were found to be higher thanthose of the healthy sheep, serum TP, ALB and glucose levels were lower. In statistical analysis, it was found that WBC,Neu and Eo values of sheep infected with Fasciola hepatica were higher when compared to WBC, Neu and Eo values in thecontrol group. In conclusion, serum haptoglobin, serum amyloid A, and fibrinogen levels were significantly higher in sheepinfected with Fasciola hepatica when compared to the healthy group. Due to the fact that increases in serum haptoglobin,serum amyloid A and fibrinogen levels in sheep with fasciolosis were similar to those observed in liver disorders, it wassuggested that these parameters could be useful in determination of the liver damage levels and prognosis and in studies onliver disorders.

【 授权许可】

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