Chest Wall PNET Masquerading as Breast Lump: A Case Report with Diagnostic Challenge

Journal of Case Reports

article

Vachaspati Kumar Mishra¹  Ajeet Kumar Gandhi¹  Madhup Rastogi¹  Satyajeet Rath¹  Akash Agarwal²  Ayushi Patni¹  Avinash Poojari¹  Nuzhat Husain³ 

[1] Radiation Oncology,Dr. Ram Manohar Lohia Institute of Medical Sciences;Surgical Oncology,Dr. Ram Manohar Lohia Institute of Medical Sciences;Pathology,Dr. Ram Manohar Lohia Institute of Medical Sciences

关键词: Biopsy;    Diagnostic Errors;    Thoracic Wall;    Neuroectodermal Tumors;    Pain.;   

DOI  :  10.17659/01.2020.0007

学科分类：生理学

来源: Journal of Case Reports

【 摘 要 】

Background: Chest wall primitive neuroectodermal tumor (PNET) is a rare tumor necessitating a prompt diagnosis. Unfortunately, the diagnosis of this tumor can be extremely challenging and misdiagnosis is at times unavoidable. CaseReport:  Here we present one such rare case of chest wall PNET. Patient initially had complaints of pain and lump in the right breast. Contrast enhanced computed tomography (CECT) of thorax showed large mass with both intra-thoracic and extra-thoracic extension. Trucut biopsy from lump was suggestive of PNET on histopathology and immunohistochemistry. Later patient was treated with induction chemotherapy with alternating VAC/IE followed by right chest wall resection. Post-operative histopathology was suggestive of complete pathological response. 18FDG PET-CT done subsequently was suggestive of complete metabolic response. Conclusion: Chest wall PNETs may mimic as breast lump, posing diagnostic dilemma. Multimodality treatment may yield excellent outcome as in our case.

【 授权许可】

Unknown