Implant surface features as key role on cell behavior

Biocell

article

RAFAEL SCAF DE MOLON¹  MARTA MARIA ALVES PEREIRA²  ERICA DORIGATTI DE AVILA² 

[1] Federal University of Rio de Janeiro;São Paulo State University

关键词: Biomaterial;    Cell adhesion;    Surface chemistry;    Surface topography;   

DOI  :  10.32604/biocell.2022.018026

学科分类：仪器

来源: Biocell

【 摘 要 】

It has been recognized that physical and chemical properties of biomaterial surfaces mediate the quality of extracellular matrix (ECM) that may affect cell behaviors. In nature, ECM is a heterogeneous three-dimensional superstructure formed by three major components, glycosaminoglycan, glycoconjugate, and protein, that anchors cellular compartments in tissues and regulates the function and the behavior of cells. Changes in the biointerface alter the quality of ECM and morphology through cell surface receptors, which, in turn, enable it to trigger specific cell signaling and different cellular responses. In fact, a number of strategies have been used to improve the functionality of surfaces and direct cell behavior through precisely designed environments. Herein, we aimed to discuss, through a science-based viewpoint, the biomaterial surface features on cell behavior and analyze the impact of cell physical modification on dental implant development.

【 授权许可】

CC BY