Honoring 50 Years of Clinical Heart Transplantation in Circulation In-Depth State-of-the-Art Review

Review

关键词: CARDIAC ALLOGRAFT VASCULOPATHY;    COMPUTED-TOMOGRAPHY ANGIOGRAPHY;    ANTIBODY-MEDIATED REJECTION;    LEFT-VENTRICULAR BYPASS;    LUNG TRANSPLANTATION;    INTERNATIONAL SOCIETY;    MYCOPHENOLATE-MOFETIL;    RANDOMIZED-TRIAL;    WORKING FORMULATION;    CONTINUOUS-FLOW;   

DOI  :  10.1161/CIRCULATIONAHA.117.029753

来源: SCIE

【 摘 要 】

Heart transplantation has become a standard therapy option for advanced heart failure. The translation of heart transplantation from innovative experiments to long-term clinical success has married prescient insights with discipline and organization in the domains of surgical techniques, organ preservation, immunosuppression, organ donation and transplantation logistics, infection control, and long-term graft surveillance. This review explores the key milestones of the past 50 years of heart transplantation and discusses current challenges and promising innovations on the clinical horizon.

【 授权许可】

Free