Coronary physiology revisited - Practical insights from the cardiac catheterization laboratory

Article

关键词: FRACTIONAL FLOW RESERVE;    DOPPLER GUIDE-WIRE;    TRANSLESIONAL PRESSURE-GRADIENT;    INTRAVASCULAR ULTRASOUND;    STENOSIS SEVERITY;    BLOOD-FLOW;    MYOCARDIAL-INFARCTION;    VELOCITY-MEASUREMENTS;    VASODILATOR RESERVE;    BALLOON ANGIOPLASTY;   

DOI  :  10.1161/01.CIR.101.11.1344

来源: SCIE

【 摘 要 】

Various coronary physiological measurements can be made in the cardiac catheterization laboratory using sensor-tipped guidewires; they include the measurement of poststenotic absolute coronary flow reserve, the relative coronary flow reserve, and the pressure-derived fractional flow reserve of the myocardium. Ambiguity regarding abnormal microcirculation has been reduced or eliminated with measurements of relative coronary flow reserve and fractional flow reserve. The role of microvascular flow impairment can be separately determined with coronary flow velocity reserve measurements. In addition to lesion assessment before and after intervention, emerging applications of coronary physiology include the determination of physiological responses to new pharmacological agents, such as glycoprotein IIb/IIIa blockers, in patients with acute myocardial infarction. Measurements of coronary physiology in the catheterization laboratory provide objective data that complement angiography for clinical decision-making.

【 授权许可】

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