Assessment of coronary arterial restenosis with phase-contrast magnetic resonance imaging measurements of coronary flow reserve

Article

关键词: BALLOON ANGIOPLASTY;    DISEASE;    ANGIOGRAPHY;    ECHOCARDIOGRAPHY;    STENOSIS;    TERM;    ADENOSINE;    ABSOLUTE;    EXERCISE;    VELOCITY;   

DOI  :  10.1161/01.CIR.101.20.2375

来源: SCIE

【 摘 要 】

Background-After successful percutaneous coronary arterial revascularization, 25% to 60% of subjects have restenosis, a recurrent coronary arterial narrowing at the site of the intervention. At present, restenosis is usually detected invasively with contrast coronary angiography. This study was performed to determine if phase-contrast MRT (PC-MRI) could be used to detect restenosis noninvasively in patients with recurrent chest pain after percutaneous-revascularization. Methods and Results-Seventeen patients (15 men, 2 women, age 36 to 77 years) with recurrent chest pain >3 months after successful percutaneous intervention underwent PC-MRI measurements of coronary artery flow reserve followed by assessments of stenosis severity with computer-assisted quantitative coronary angiography. The intervention was performed in the left anterior descending coronary artery in 15 patients, one of its diagonal branches in 2 patients, and the right coronary artery in 1 patient. A PC-MRI coronary flow reserve value less than or equal to 2.0 was 100% and 82% sensitive and 89% and 100% specific for detecting a luminal diameter narrowing of greater than or equal to 70% and greater than or equal to 50%, respectively. Conclusions-Assessments of coronary flow reserve with PC-MRI can be used to identify flow-limiting stenoses (luminal diameter narrowings >70%) in patients with recurrent chest pain in the months after a successful percutaneous intervention.

【 授权许可】

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