Acute respiratory distress syndrome

Review

关键词: ACUTE LUNG INJURY;    TIDAL-VOLUME VENTILATION;    END-EXPIRATORY PRESSURE;    HIGH-FREQUENCY OSCILLATION;    CONTROLLED CLINICAL-TRIAL;    CARE-UNIT MORTALITY;    PULMONARY-ARTERY;    MECHANICAL VENTILATION;    RECRUITMENT MANEUVERS;    PRONE POSITION;   

DOI  :  10.1016/S0140-6736(16)00578-X

来源: SCIE

【 摘 要 】

Acute respiratory distress syndrome presents as hypoxia and bilateral pulmonary infiltrates on chest imaging in the absence of heart failure sufficient to account for this clinical state. Management is largely supportive, and is focused on protective mechanical ventilation and the avoidance of fluid overload. Patients with severe hypoxaemia can be managed with early short-term use of neuromuscular blockade, prone position ventilation, or extracorporeal membrane oxygenation. The use of inhaled nitric oxide is rarely indicated and both beta(2) agonists and late corticosteroids should be avoided. Mortality remains at approximately 30%.

【 授权许可】

Free