Type 1 diabetes

Article

关键词: STEM-CELL TRANSPLANTATION;    INSULIN-PUMP THERAPY;    DOUBLE-BLIND;    C-PEPTIDE;    COMPLICATIONS-TRIAL/EPIDEMIOLOGY;    CARDIOVASCULAR-DISEASE;    NOCTURNAL HYPOGLYCEMIA;    GENETIC SUSCEPTIBILITY;    ISLET TRANSPLANTATION;    ARTIFICIAL PANCREAS;   

DOI  :  10.1016/S0140-6736(13)60591-7

来源: SCIE

【 摘 要 】

Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes has grown substantially, particularly with regard to disease prediction and heterogeneity, pancreatic pathology, and epidemiology. Technological improvements in insulin pumps and continuous glucose monitors help patients with type 1 diabetes manage the challenge of lifelong insulin administration. Agents that show promise for averting debilitating disease-associated complications have also been identifi ed. However, despite broad organisational, intellectual, and fi scal investments, no means for preventing or curing type 1 diabetes exists, and, globally, the quality of diabetes management remains uneven. This Seminar discusses current progress in epidemiology, pathology, diagnosis, and treatment of type 1 diabetes, and prospects for an improved future for individuals with this disease.

【 授权许可】

Free