Stress hyperglycaemia

Review

关键词: ACUTE MYOCARDIAL-INFARCTION;    INTENSIVE INSULIN THERAPY;    BLOOD-GLUCOSE CONTROL;    TRANSPORTER MESSENGER-RNA;    CRITICALLY-ILL PATIENTS;    LONG-TERM MORTALITY;    PROTEIN-KINASE-C;    OXIDATIVE STRESS;    GLYCEMIC CONTROL;    ADMISSION HYPERGLYCEMIA;   

DOI  :  10.1016/S0140-6736(09)60553-5

来源: SCIE

【 摘 要 】

Results of randomised controlled trials of tight glycaemic control in hospital inpatients might vary with population and disease state. Individualised therapy for different hospital inpatient populations and identification of patients at risk of hyperglycaemia might be needed. One risk factor that has received much attention is the presence of pre-existing diabetes. So-called stress hyperglycaemia, is usually defined as hyperglycaemia resolving spontaneously after dissipation of acute illness. The term generally refers to patients without known diabetes, although patients with diabetes might also develop stress hyperglycaemia-a fact overlooked in many studies comparing hospital inpatients with or without diabetes. investigators of several studies have suggested that patients with stress hyperglycaemia are at higher risk of adverse consequences than are those with pre-existing diabetes. We describe classification of stress hyperglycaemia, mechanisms of harm, and management strategies.

【 授权许可】

Free