CYSTICERCOSIS AS A MAJOR CAUSE OF EPILEPSY IN PERU

Article

关键词: CEREBRAL CYSTICERCOSIS;    TAENIA-SOLIUM;    DIAGNOSIS;    ASSAY;    NEUROCYSTICERCOSIS;    ANTIGENS;    ELISA;   

DOI  :  10.1016/0140-6736(93)90064-N

来源: SCIE

【 摘 要 】

In countries where cysticercosis is endemic, the proportion of epilepsy due to cysticercosis is not well documented. To investigate the association between cysticercosis and epilepsy, we used the enzyme-linked immunoelectrotransfer blot (EITB) assay to detect serum antibodies to Taenia solium in 498 consecutive outpatients at a neurology clinic in Lima, Peru. Every patient was classified as epileptic (n = 189) or non-epileptic (n = 309) after neurological, and where possible electroencephalographic, examination. A substantially higher proportion of epileptic than non-epileptic patients was seropositive in the EITB (22 [12%] vs 8 [3%], p<0.001). 19% of epileptic patients born outside Lima, 20% of those with late-onset epilepsy, and 29% of patients with both these characteristics were seropositive. Thus, in Peru, cysticercosis is an important aetiological factor for epilepsy.

【 授权许可】

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