A speech planning network for interactive language use

Article

关键词: HUMAN CEREBRAL-CORTEX;    TURN-TAKING;    BROCAS AREA;    REGIONS;    ORGANIZATION;    APRAXIA;   

DOI  :  10.1038/s41586-021-04270-z

来源: SCIE

【 摘 要 】

During conversation, people take turns speaking by rapidly responding to their partners while simultaneously avoiding interruption(1,2). Such interactions display a remarkable degree of coordination, as gaps between turns are typically about 200 milliseconds(3)-approximately the duration of an eyeblink(4). These latencies are considerably shorter than those observed in simple word-production tasks, which indicates that speakers often plan their responses while listening to their partners(2). Although a distributed network of brain regions has been implicated in speech planning(5-9), the neural dynamics underlying the specific preparatory processes that enable rapid turn-taking are poorly understood. Here we use intracranial electrocorticography to precisely measure neural activity as participants perform interactive tasks, and we observe a functionally and anatomically distinct class of planning-related cortical dynamics. We localize these responses to a frontotemporal circuit centred on the language-critical caudal inferior frontal cortex(10) (Broca's region) and the caudal middle frontal gyrus-a region not normally implicated in speech planning(11-13). Using a series of motor tasks, we then show that this planning network is more active when preparing speech as opposed to non-linguistic actions. Finally, we delineate planning-related circuitry during natural conversation that is nearly identical to the network mapped with our interactive tasks, and we find this circuit to be most active before participant speech during unconstrained turn-taking. Therefore, we have identified a speech planning network that is central to natural language generation during social interaction.During conversation, people take turns speaking by rapidly responding to their partners while simultaneously avoiding interruption(1,2). Such interactions display a remarkable degree of coordination, as gaps between turns are typically about 200 milliseconds(3)-approximately the duration of an eyeblink(4). These latencies are considerably shorter than those observed in simple word-production tasks, which indicates that speakers often plan their responses while listening to their partners(2). Although a distributed network of brain regions has been implicated in speech planning(5-9), the neural dynamics underlying the specific preparatory processes that enable rapid turn-taking are poorly understood. Here we use intracranial electrocorticography to precisely measure neural activity as participants perform interactive tasks, and we observe a functionally and anatomically distinct class of planning-related cortical dynamics. We localize these responses to a frontotemporal circuit centred on the language-critical caudal inferior frontal cortex(10) (Broca's region) and the caudal middle frontal gyrus-a region not normally implicated in speech planning(11-13). Using a series of motor tasks, we then show that this planning network is more active when preparing speech as opposed to non-linguistic actions. Finally, we delineate planning-related circuitry during natural conversation that is nearly identical to the network mapped with our interactive tasks, and we find this circuit to be most active before participant speech during unconstrained turn-taking. Therefore, we have identified a speech planning network that is central to natural language generation during social interaction. During conversation, people take turns speaking by rapidly responding to their partners while simultaneously avoiding interruption(1,2). Such interactions display a remarkable degree of coordination, as gaps between turns are typically about 200 milliseconds(3)-approximately the duration of an eyeblink(4). These latencies are considerably shorter than those observed in simple word-production tasks, which indicates that speakers often plan their responses while listening to their partners(2). Although a distributed network of brain regions has been implicated in speech planning(5-9), the neural dynamics underlying the specific preparatory processes that enable rapid turn-taking are poorly understood. Here we use intracranial electrocorticography to precisely measure neural activity as participants perform interactive tasks, and we observe a functionally and anatomically distinct class of planning-related cortical dynamics. We localize these responses to a frontotemporal circuit centred on the language-critical caudal inferior frontal cortex(10) (Broca's region) and the caudal middle frontal gyrus-a region not normally implicated in speech planning(11-13). Using a series of motor tasks, we then show that this planning network is more active when preparing speech as opposed to non-linguistic actions. Finally, we delineate planning-related circuitry during natural conversation that is nearly identical to the network mapped with our interactive tasks, and we find this circuit to be most active before participant speech during unconstrained turn-taking. Therefore, we have identified a speech planning network that is central to natural language generation during social interaction.During conversation, people take turns speaking by rapidly responding to their partners while simultaneously avoiding interruption(1,2). Such interactions display a remarkable degree of coordination, as gaps between turns are typically about 200 milliseconds(3)-approximately the duration of an eyeblink(4). These latencies are considerably shorter than those observed in simple word-production tasks, which indicates that speakers often plan their responses while listening to their partners(2). Although a distributed network of brain regions has been implicated in speech planning(5-9), the neural dynamics underlying the specific preparatory processes that enable rapid turn-taking are poorly understood. Here we use intracranial electrocorticography to precisely measure neural activity as participants perform interactive tasks, and we observe a functionally and anatomically distinct class of planning-related cortical dynamics. We localize these responses to a frontotemporal circuit centred on the language-critical caudal inferior frontal cortex(10) (Broca's region) and the caudal middle frontal gyrus-a region not normally implicated in speech planning(11-13). Using a series of motor tasks, we then show that this planning network is more active when preparing speech as opposed to non-linguistic actions. Finally, we delineate planning-related circuitry during natural conversation that is nearly identical to the network mapped with our interactive tasks, and we find this circuit to be most active before participant speech during unconstrained turn-taking. Therefore, we have identified a speech planning network that is central to natural language generation during social interaction. During conversation, people take turns speaking by rapidly responding to their partners while simultaneously avoiding interruption(1,2). Such interactions display a remarkable degree of coordination, as gaps between turns are typically about 200 milliseconds(3)-approximately the duration of an eyeblink(4). These latencies are considerably shorter than those observed in simple word-production tasks, which indicates that speakers often plan their responses while listening to their partners(2). Although a distributed network of brain regions has been implicated in speech planning(5-9), the neural dynamics underlying the specific preparatory processes that enable rapid turn-taking are poorly understood. Here we use intracranial electrocorticography to precisely measure neural activity as participants perform interactive tasks, and we observe a functionally and anatomically distinct class of planning-related cortical dynamics. We localize these responses to a frontotemporal circuit centred on the language-critical caudal inferior frontal cortex(10) (Broca's region) and the caudal middle frontal gyrus-a region not normally implicated in speech planning(11-13). Using a series of motor tasks, we then show that this planning network is more active when preparing speech as opposed to non-linguistic actions. Finally, we delineate planning-related circuitry during natural conversation that is nearly identical to the network mapped with our interactive tasks, and we find this circuit to be most active before participant speech during unconstrained turn-taking. Therefore, we have identified a speech planning network that is central to natural language generation during social interaction.

【 授权许可】

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