Enabling the chemistry of life (vol 409, pg 226, 2001)

Correction

关键词: CATALYSIS;    ENZYMES;    DNA;    SYNTHETASE;    EVOLUTION;    BIOSYNTHESIS;    POLYKETIDE;    SYNTHASE;    PATHWAYS;    PROTEINS;   

DOI  :  10.1038/35081124

来源: SCIE

【 摘 要 】

Enzymes are the subset of proteins that catalyse the chemistry of life, transforming both macromolecular substrates and small molecules. The precise three-dimensional architecture of enzymes permits almost unerring selectivity in physical and chemical steps to impose remarkable rate accelerations and specificity in product-determining reactions. Many enzymes are members of families that carry out related chemical transformations and offer opportunities for directed in vitro evolution, to tailor catalytic properties to particular functions.

【 授权许可】

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