Sex releases the speed limit on evolution

Article

关键词: TERM EXPERIMENTAL EVOLUTION;    ESCHERICHIA-COLI;    RECOMBINATION;    SELECTION;    ADAPTATION;   

DOI  :  10.1038/nature01191

来源: SCIE

【 摘 要 】

Explaining the evolutionary maintenance of sex remains a key problem in evolutionary biology(1-3). One potential benefit of sex is that it may allow a more rapid adaptive response when environmental conditions change, by increasing the efficiency with which selection can fix beneficial mutations(4-7). Here I show that sex can increase the rate of adaptation in the facultatively sexual single-celled chlorophyte Chlamydomonas reinhardtii, but that the benefits of sex depend crucially on the size of the population that is adapting: sex has a marked effect in large populations but little effect in small populations. Several mechanisms have been proposed to explain the benefits of sex in a novel environment, including stochastic effects in small populations, clonal interference and epistasis between beneficial alleles. These results indicate that clonal interference is important in this system.

【 授权许可】

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