Somatic cell nuclear transfer

Article

关键词: FIBROBLAST CELLS;    DNA METHYLATION;    MOUSE CLONING;    CLONED MICE;    EMBRYOS;    CALVES;    FETAL;    EXPRESSION;    CYTOPLASM;    METAPHASE;   

DOI  :  10.1038/nature01079

来源: SCIE

【 摘 要 】

Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.

【 授权许可】

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