Host factors and the pathogenesis of HIV-induced disease

Review

关键词: HUMAN-IMMUNODEFICIENCY-VIRUS;    TUMOR-NECROSIS-FACTOR;    NF-KAPPA-B;    TYPE-1 INFECTION;    IMMUNE-RESPONSE;    FACTOR-ALPHA;    PERIPHERAL-BLOOD;    HOMOSEXUAL MEN;    CELL-LINE;    IN-VIVO;   

DOI  :  10.1038/384529a0

来源: SCIE

【 摘 要 】

The level of human immunodeficiency virus (HIV) replication in patients reflects a balance between stimulatory and inhibitory host factors (particularly endogenous cytokines). New information concerning the cellular co-receptors for HIV and the cellular tropism of different strains of virus will advance our understanding of HIV-induced pathogenesis and suggests new therapeutic and preventive strategies.

【 授权许可】

Free