Diversity, stability and resilience of the human gut microbiota

Review

关键词: INFLAMMATORY-BOWEL-DISEASE;    INTESTINAL MICROBIOTA;    CLOSTRIDIUM-DIFFICILE;    CROHNS-DISEASE;    ANTIBIOTIC-TREATMENT;    MOLECULAR ANALYSIS;    FECAL MICROBIOTA;    BODY HABITATS;    SEQUENCE DATA;    HUMAN COLON;   

DOI  :  10.1038/nature11550

来源: SCIE

【 摘 要 】

Trillions of microbes inhabit the human intestine, forming a complex ecological community that influences normal physiology and susceptibility to disease through its collective metabolic activities and host interactions. Understanding the factors that underlie changes in the composition and function of the gut microbiota will aid in the design of therapies that target it. This goal is formidable. The gut microbiota is immensely diverse, varies between individuals and can fluctuate over time - especially during disease and early development. Viewing the microbiota from an ecological perspective could provide insight into how to promote health by targeting this microbial community in clinical treatments.

【 授权许可】

Free