Initial impact of the sequencing of the human genome

Review

关键词: HAPLOTYPE STRUCTURE;    FETAL-HEMOGLOBIN;    WIDE ASSOCIATION;    SMALL MOLECULES;    GENE;    MUTATIONS;    EXPRESSION;    REVEALS;    CANCER;    LOCI;   

DOI  :  10.1038/nature09792

来源: SCIE

【 摘 要 】

The sequence of the human genome has dramatically accelerated biomedical research. Here I explore its impact, in the decade since its publication, on our understanding of the biological functions encoded in the genome, on the biological basis of inherited diseases and cancer, and on the evolution and history of the human species. I also discuss the road ahead in fulfilling the promise of genomics for medicine.

【 授权许可】

Free