The CONFIDENT study protocol: a randomized controlled trial comparing two methods to increase long-term care worker confidence in the COVID-19 vaccines

BMC Public Health

Study Protocol

Eve Dubé¹  Timothy Holahan²  Peter Schmidt³  N. Ruth Little⁴  Don Goldmann⁵  Rowena Sheppard⁶  Branden Fillbrook⁷  Celeste Wooten⁸  Matthew Cantrell⁹  A. James O’Malley^1,10  Jacqueline A. Pogue^1,11  Catherine H. Saunders^1,11  Gabrielle Stevens^1,11  Ailyn Sierpe^1,11  Rachael P. Thomeer^1,11  Danielle C. Schubbe^1,11  Lisa C. Johnson^1,11  Glyn Elwyn^1,11  Renata W. Yen^1,11  Rachel C. Forcino^1,11  Marie-Anne Durand^1,12 

[1] Department of Anthropology, Faculty of Social Sciences, Laval University, Quebec City, QC, Canada;Department of Geriatric Medicine, University of Rochester, Rochester, NY, US;Department of Neurology, Grossman School of Medicine, New York University, New York, NY, US;Department of Public Health, Brody School of Medicine, East Carolina University, Greenville, NC, US;Institute for Healthcare Improvement, Boston, MA, US;Long-term care worker partner, Maynardville, TN, US;Long-term care worker partner, Romeo, MI, US;Long-term care worker partner, Virginia Beach, VA, US;National Association of Health Care Assistants, Carl Junction, MO, US;The Dartmouth Institute for Health Policy & Clinical Practice, Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, NH, US;The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine, Dartmouth College, Lebanon, NH, US;The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine, Dartmouth College, Lebanon, NH, US;Unisanté, Centre universitaire de médecine générale et santé publique, Rue du Bugnon 44, Lausanne, Switzerland;CERPOP, Université de Toulouse, Inserm, Toulouse, UPS, France;

关键词: COVID-19;    COVID-19 vaccines;    Vaccine confidence;    Vaccine hesitancy;    Long-term care workers;    Intervention;    Social media;    Dialogue-based;    Shared decision-making;    Trial protocol;   

DOI  :  10.1186/s12889-023-15266-x

 received in 2022-12-20, accepted in 2023-02-13,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundClinical and real-world effectiveness data for the COVID-19 vaccines have shown that they are the best defense in preventing severe illness and death throughout the pandemic. However, in the US, some groups remain more hesitant than others about receiving COVID-19 vaccines. One important group is long-term care workers (LTCWs), especially because they risk infecting the vulnerable and clinically complex populations they serve. There is a lack of research about how best to increase vaccine confidence, especially in frontline LTCWs and healthcare staff. Our aims are to: (1) compare the impact of two interventions delivered online to enhanced usual practice on LTCW COVID-19 vaccine confidence and other pre-specified secondary outcomes, (2) determine if LTCWs’ characteristics and other factors mediate and moderate the interventions’ effect on study outcomes, and (3) explore the implementation characteristics, contexts, and processes needed to sustain a wider use of the interventions.MethodsWe will conduct a three-arm randomized controlled effectiveness-implementation hybrid (type 2) trial, with randomization at the participant level. Arm 1 is a dialogue-based webinar intervention facilitated by a LTCW and a medical expert and guided by an evidence-based COVID-19 vaccine decision tool. Arm 2 is a curated social media web application intervention featuring interactive, dynamic content about COVID-19 and relevant vaccines. Arm 3 is enhanced usual practice, which directs participants to online public health information about COVID-19 vaccines. Participants will be recruited via online posts and advertisements, email invitations, and in-person visits to care settings. Trial data will be collected at four time points using online surveys. The primary outcome is COVID-19 vaccine confidence. Secondary outcomes include vaccine uptake, vaccine and booster intent for those unvaccinated, likelihood of recommending vaccination (both initial series and booster), feeling informed about the vaccines, identification of vaccine information and misinformation, and trust in COVID-19 vaccine information provided by different people and organizations. Exploration of intervention implementation will involve interviews with study participants and other stakeholders, an in-depth process evaluation, and testing during a subsequent sustainability phase.DiscussionStudy findings will contribute new knowledge about how to increase COVID-19 vaccine confidence and effective informational modalities for LTCWs.Trial registrationNCT05168800 at ClinicalTrials.gov, registered December 23, 2021.

【 授权许可】

CC BY   
© The Author(s) 2023

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