Risk of iatrogenic pneumothorax based on location of transbronchial biopsy: a retrospective cohort study

BMC Research Notes

Research Note

Mina Ishak¹  Debarati Chakraborty¹  Shayan Kassirian¹  Michael A. Mitchell¹  Inderdeep Dhaliwal¹ 

[1] Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada;

关键词: Pneumothorax;    Transbronchial biopsy;    Bronchoscopy;   

DOI  :  10.1186/s13104-023-06275-5

 received in 2022-06-20, accepted in 2023-01-17,  发布年份 2023

来源: Springer

【 摘 要 】

ObjectiveTransbronchial lung biopsy (TBB) is a commonly performed procedure to obtain parenchymal lung tissue during bronchoscopy. Pneumothorax is among the most common serious complications of TBB. The objective of this study was to assess whether location of TBB correlated with development of post-procedural pneumothorax. We also sought to identify additional risk factors associated with pneumothorax development.This was a single-centre, retrospective cohort study. All TBB performed between 2010 and 2020 underwent subsequent chart review. The primary outcome was radiologist reported pneumothorax on post-procedure chest x-ray. Multivariable logistic regression model was created with included variables chosen a priori based on clinical significance.ResultsThere were a total of 222 TBB performed that met inclusion criteria. Radiographic evidence of pneumothorax was reported in 38 patients (15.4%). Ten patients (4.1%) required a chest tube. In the multivariable analysis, risk of pneumothorax was significantly higher for biopsies obtained from the left upper lobe (OR 3.3; 95% CI 1.3–9.1). There was an increased risk of pneumothorax following TBB when obtained from the left upper lobe. Clinicians should be aware of the increased risk and should consider alternative locations in patients with diffuse lung disease.

【 授权许可】

CC BY   
© Crown 2023