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Cell Communication and Signaling
A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology
Methodology
Christos Gatsogiannis1  Minghao Chen1  Clarissa L. Waites2  Martina Samiotaki3  George Stamatakis3  George Panayotou3  Foteini Tzouanou4  Carlos Nogueras-Ortiz5  Dimitrios Kapogiannis5  Liliana Santos6  Patrícia A. Gomes6  Bárbara Coimbra6  Carina Soares-Cunha6  Nuno Sousa6  Joana M. Silva6  Ioannis Sotiropoulos7  Cristian Bodo8  Bruno Costa-Silva8 
[1] Center for Soft Nanoscience and Institute of Medical Physics and Biophysics, University of Muenster, 48149, Münster, Germany;Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, 44227, Dortmund, Germany;Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA;Institute for Bioinnovation, Biomedical Sciences Research Center “Alexander Fleming”, 16672, Vari, Attica, Greece;Institute of Biosciences and Applications NCSR “Demokritos”, Athens, Greece;Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, NIH, Baltimore, MD, USA;Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal;ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal;Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal;ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal;Institute of Biosciences and Applications NCSR “Demokritos”, Athens, Greece;Systems Oncology Group, Champalimaud Research, Champalimaud Centre for the Unknown, Av. Brasília, 1400-038, Lisbon, Portugal;
关键词: Extracellular vesicles;    Brain;    Exosomes;    Human;    Mouse;    Spontaneous release;    Stress;   
DOI  :  10.1186/s12964-023-01045-z
 received in 2022-09-29, accepted in 2023-01-08,  发布年份 2023
来源: Springer
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【 授权许可】

CC BY   
© The Author(s) 2023

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