Endocrine complications of anorexia nervosa

Journal of Eating Disorders

Review

Melanie S. Haines¹ 

[1]Neuroendocrine Unit, Massachusetts General Hospital, 50 Staniford Street, Suite 750B, 02114, Boston, MA, USA

[2]Harvard Medical School, Boston, MA, USA

关键词: Anorexia nervosa;    Endocrine complications;    Amenorrhea;    Low bone density;   

DOI  :  10.1186/s40337-023-00744-9

 received in 2022-12-21, accepted in 2023-02-02,  发布年份 2023

来源: Springer

【 摘 要 】

An important component in the treatment of anorexia nervosa (AN) is the evaluation and management of its endocrine complications, including functional hypogonadotropic hypogonadism and increased fracture risk. The body’s adaptive response to chronic starvation results in many endocrine abnormalities, most of which are reversible upon weight restoration. A multidisciplinary team with experience in treating patients with AN is critical to improving endocrine outcomes in patients with this disorder, including in women with AN who are interested in fertility. Much less is understood about endocrine abnormalities in men, as well as sexual and gender minorities, with AN. In this article, we review the pathophysiology and evidence-based recommendations for the treatment of endocrine complications in AN, as well as discuss the status of clinical research in this area.

【 授权许可】

CC BY   
© The Author(s) 2023