Assessment of vitamin D among male adolescents and young adults hospitalized with eating disorders

Journal of Eating Disorders

Research

Anthony Nguyen¹  Jason M. Nagata¹  Khushi P. Patel¹  Vanessa I. Machen¹  Andrea K. Garber¹  Sara M. Buckelew¹  Anna Grandis¹  Amanda E. Downey²  Kyle T. Ganson³  Paola Bojorquez-Ramirez⁴ 

[1]Department of Pediatrics, University of California, Box 0110, 550 16th Street, 4th Floor, 94143, San Francisco, CA, USA

[2]Department of Pediatrics, University of California, Box 0110, 550 16th Street, 4th Floor, 94143, San Francisco, CA, USA

[3]Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, 94143, San Francisco, CA, USA

[4]Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON, Canada

[5]Yale School of Public Health, Yale University, 06510, New Haven, CT, USA

关键词: Feeding and eating disorders;    Male;    Boys;    Vitamin D;    Adolescent;   

DOI  :  10.1186/s40337-022-00627-5

 received in 2022-05-01, accepted in 2022-06-29,  发布年份 2022

来源: Springer

【 摘 要 】

PurposeMedical complications of eating disorders in males are understudied compared to females, as is the case of vitamin D deficiency. The aim of this study was to assess vitamin D levels among male and female adolescents and young adults hospitalized for medical complications of eating disorders.MethodsWe retrospectively reviewed electronic medical records of patients aged 9–25 years (N = 565) admitted to the University of California, San Francisco Eating Disorders Program for medical instability, between May 2012 and August 2020. Serum vitamin D (25-hydroxy) level was assessed at admission as was history of prior calcium, vitamin D, or multivitamin supplementation. Linear regression was used to assess factors associated with vitamin D levels.ResultsA total of 93 males and 472 females met eligibility criteria (age 15.5 ± 2.8, 58.8% anorexia nervosa; admission body mass index 17.6 ± 2.91). Among male participants, 44.1% had 25-hydroxyvitamin D levels < 30 ng/mL, 18.3% had 25-hydroxyvitamin D levels < 20 ng/mL, and 8.6% had 25-hydroxyvitamin D levels < 12 ng/mL. There were no significant differences in 25-hydroxyvitamin D levels in males compared to females, except that a lower proportion (1.9%) of female participants had 25-hydroxyvitamin D levels < 12 ng/mL (p = 0.001). Only 3.2% of males reported calcium or vitamin D-specific supplementation prior to hospital admission, while 8.6% reported taking multivitamins. White race, prior calcium/vitamin D supplementation, and higher calcium levels were associated with higher vitamin D levels on admission.ConclusionsNearly half of patients admitted to the hospital for malnutrition secondary to eating disorders presented with low 25-hydroxyvitamin D levels; males were more likely than females to have severe vitamin D deficiency. These findings support vitamin D assessment as part of the routine medical/nutritional evaluation for hospitalized eating disorder patients, with particular attention on male populations.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

Fig. 7