Nonrestorative sleep is a risk factor for metabolic syndrome in the general Japanese population

Diabetology & Metabolic Syndrome

Research

Katsutoshi Tanaka¹  Masahiro Suzuki²  Yoshiyuki Kaneko²  Kenichi Kuriyama³  Yuichiro Otsuka⁴  Yoshitaka Kaneita⁴  Osamu Itani⁴  Yuuki Matsumoto⁴ 

[1] Department of Occupational Mental Health, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, 252-0374, Minami, Sagamihara, Japan;Department of Psychiatry, Nihon University School of Medicine, 30-1 Oyaguchi-Kamimachi, Itabashi-Ku, 173-8610, Tokyo, Japan;Department of Sleep-Wake Disorders, National Center of Neurology and Psychiatry, National Institute of Mental Health, 4-1-1 Ogawa-Higashi, 187-8553, Kodaira, Tokyo, Japan;Division of Public Health, Department of Social Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-Kamimachi, Itabashi-Ku, 173-8610, Tokyo, Japan;

关键词: Cardiovascular risk;    Diabetes;    Hypertension;    Metabolic syndrome;    Sleep;   

DOI  :  10.1186/s13098-023-00999-x

 received in 2022-12-13, accepted in 2023-02-15,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundThis longitudinal study aimed to investigate the effects of nonrestorative sleep on developing metabolic syndrome (MetS) and related diseases in a general Japanese middle-aged population.MethodsOverall, 83,224 adults without MetS (mean age: 51.5 ± 3.5 years) from the Health Insurance Association in Japan were followed up for a maximum of 8 years between 2011 and 2019. The Cox proportional hazard method was used to determine whether nonrestorative sleep, assessed using a single-item question, was significantly associated with the respective development of MetS, obesity, hypertension, diabetes, and dyslipidemia. The MetS criteria were adopted by the Examination Committee for Criteria of Metabolic Syndrome in Japan.ResultsThe mean follow-up duration was 6.0 years. The incidence rate of MetS was 50.1 person-years/1,000 during the study period. Data suggested that nonrestorative sleep was associated with MetS (hazard ratio [HR]: 1.12, 95% confidence interval [CI]: 1.08–1.16) and other disorders, such as obesity (HR: 1.07, 95% CI: 1.02–1.12), hypertension (HR: 1.07, 95% CI: 1.04–1.11), and diabetes (HR: 1.07, 95% CI: 1.01–1.12) but not with dyslipidemia (HR: 1.00, 95% CI: 0.97–1.03).ConclusionsNonrestorative sleep is associated with the development of MetS and many of its core components in the middle-aged Japanese population. Therefore, assessing nonrestorative sleep may help identify individuals at a risk of MetS development.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

Fig. 6