PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control

Molecular Medicine

Research Article

Xijing Zhang¹  Longwang Chen²  Zhongqiu Lu²  Zhimin Qiu²  Guangju Zhao²  You Wu³ 

[1] Department of Critical Care Medicine, Xijing Hospital, 710000, Xi’an, Shaanxi, China;Department of Emergency, First Affiliated Hospital of Wenzhou Medical University, Shangcai Road, Ouhai District, 325000, Wenzhou, Zhejiang, China;Department of Emergency, First Affiliated Hospital of Wenzhou Medical University, Shangcai Road, Ouhai District, 325000, Wenzhou, Zhejiang, China;Department of Critical Care Medicine, Xijing Hospital, 710000, Xi’an, Shaanxi, China;

关键词: Sepsis;    Dendritic cells;    PINK1;    Mitophagy;    Mitochondrial fission;    Mitochondrial quality control;   

DOI  :  10.1186/s10020-023-00618-5

 received in 2022-07-08, accepted in 2023-02-10,  发布年份 2023

来源: Springer

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

13690_2023_1029_Article_IEq18.gif

13690_2023_1029_Article_IEq12.gif

13690_2023_1029_Article_IEq8.gif

Fig. 1

Fig. 1

Fig. 3

Fig. 1

12936_2023_4483_Article_IEq15.gif

Fig. 2

Fig. 3