Emerging 3D bioprinting applications in plastic surgery

Biomaterials Research

Review

Pu Yang¹  Bairong Fang¹  Yikun Ju¹  Xiaoyan Xie²  Lanjie Lei³  Yue Hu⁴ 

[1] Department of Plastic and Aesthetic (Burn) Surgery, The Second Xiangya Hospital, Central South University, 410011, Changsha, People’s Republic of China;Department of Stomatology, The Second Xiangya Hospital, Central South University, 410011, Changsha, People’s Republic of China;School of Biological Science and Medical Engineering, Southeast University, 210096, Nanjing, People’s Republic of China;School of Clinical Medicine, North Sichuan Medical College, 637000, Nanchong, People’s Republic of China;

关键词: Plastic surgery;    Biomaterials;    3D bioprinting;    Tissue engineering;    Tissue regeneration;   

DOI  :  10.1186/s40824-022-00338-7

 received in 2022-11-11, accepted in 2022-12-14,  发布年份 2022

来源: Springer

【 摘 要 】

Plastic surgery is a discipline that uses surgical methods or tissue transplantation to repair, reconstruct and beautify the defects and deformities of human tissues and organs. Three-dimensional (3D) bioprinting has gained widespread attention because it enables fine customization of the implants in the patient's surgical area preoperatively while avoiding some of the adverse reactions and complications of traditional surgical approaches. In this paper, we review the recent research advances in the application of 3D bioprinting in plastic surgery. We first introduce the printing process and basic principles of 3D bioprinting technology, revealing the advantages and disadvantages of different bioprinting technologies. Then, we describe the currently available bioprinting materials, and dissect the rationale for special dynamic 3D bioprinting (4D bioprinting) that is achieved by varying the combination strategy of bioprinting materials. Later, we focus on the viable clinical applications and effects of 3D bioprinting in plastic surgery. Finally, we summarize and discuss the challenges and prospects for the application of 3D bioprinting in plastic surgery. We believe that this review can contribute to further development of 3D bioprinting in plastic surgery and provide lessons for related research.Graphical Abstract

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

41116_2022_35_Article_IEq557.gif

Fig. 1

Fig. 31

41116_2022_35_Article_IEq489.gif

Fig. 5

Fig. 2

Fig. 17

41116_2022_35_Article_IEq446.gif

41116_2022_35_Article_IEq440.gif