期刊论文详细信息
BMC Nephrology | |
Peritoneal dialysis related eosinophilic peritonitis: a case report and review of the literature | |
Case Report | |
Xia Yangyang1  Zhang Miao1  Zhang Qingyan1  Jiang Chunming1  | |
[1]Department of Nephrology, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, 321 Zhongshan Road, 210008, Nanjing, China | |
关键词: Eosinophilic peritonitis; Peritoneal dialysis; Peritonitis; Infection; Case report; | |
DOI : 10.1186/s12882-022-03027-8 | |
received in 2021-11-23, accepted in 2022-11-30, 发布年份 2022 | |
来源: Springer | |
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【 摘 要 】
BackgroundOvert eosinophilic peritonitis (EP) is a relatively uncommon complication of peritoneal dialysis (PD), although not rare. Here we reported a case of EP relieved after changing dialysate. Case presentationA 28-year old male patient developed cloudy PD effluents within the first month after PD started. Cytological study of PD effluents showed elevated white blood cells and polynuclear cells. Bacteria culture of PD effluents repeated for several times were all negative, and no pathogen was found by metagenomics next generation sequencing (mNGS). Antibiotic therapy for 28-day was ineffective. Based on these and increased eosinophils in peritoneal fluid, he was finally diagnosed as EP. PD dialysate was changed (consists of the same buffer agent and electrolytes, but is packed in bags that do not contain PVC), and the patient’s PD effluent became clear. Of note, EP did not relapse 5 months later when the patient started to use the former PD solution again.ConclusionAlthough PD effluent turbidity almost always represents infectious peritonitis, there are other differential diagnoses including EP. For patients with cloudy fluid accompanied by mild symptoms who do not response to antibiotic therapy, it is reasonable to consider the possibility of this disease. EP tends to heal spontaneously, however, antihistamines or glucocorticoids are required sometimes to avoid catheter obstruction. For patients with no obvious incentives, replacement of dialysate may be useful.【 授权许可】
CC BY
© The Author(s) 2023
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