Key design elements of successful acute ischemic stroke treatment trials

Neurological Research and Practice

Review

L. Yperzeele¹  I. Koltsov²  Y. V. Venugopalan³  M. V. Mazya⁴  W. Hacke⁵  S. Chapman⁶  M. Charalambous⁷  A. Shoamanesh⁸  P. M. Bath⁹  V. Caso^1,10 

[1] Antwerp NeuroVascular Center and Stroke Unit, Department of Neurology, University Hospital Antwerp, Edegem, Belgium;Translational Neurosciences Research Group, Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium;Cerebrovascular Diseases Laboratory, Pirogov Russian National Research Medical University, Moscow, Russia;Neurology, Neurosurgery, and Medical Genetics Department, Pirogov Russian National Research Medical University, Moscow, Russia;Neuroimmunology Department, Federal Center of Brain Research and Neurotechnologies, Moscow, Russia;Department of Neurology, All India Institute of Medical Sciences, New Delhi, India;Department of Neurology, Karolinska University Hospital, Stockholm, Sweden;Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden;Department of Neurology, Ruprechts Karl University, Heidelberg, Germany;Department of Neurology, University of Virginia, Charlottesville, USA;Department of Rehabilitation Sciences, Cyprus University of Technology, Limassol, Cyprus;Laboratory of Cognitive and Neurological Sciences, Neurology Unit, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland;Division of Neurology, McMaster University / Population Health Research Institute, Hamilton, Canada;Stroke Trials Unit, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK;Stroke Unit, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy;

关键词: Acute stroke care;    Randomized controlled trials;    Trial design;    Stroke;    Acute stroke therapy;    Stroke research;   

DOI  :  10.1186/s42466-022-00221-9

 received in 2022-08-16, accepted in 2022-10-17,  发布年份 2022

来源: Springer

【 授权许可】

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© The Author(s) 2023